A: No. Kenshi does not disable achievements for using the debug or editor tools.
Treat the F12 key like a skeleton in the Black Desert City—dangerous if mishandled, but priceless if you know how to talk to it. kenshi f12
Here is the breakdown of what "Kenshi F12" actually does and why you need to use it carefully. If you press F12 while playing Kenshi (and you haven't remapped your keys), you are not taking a screenshot (that’s typically F11 in Steam). Instead, you are opening the Forgotten Construction Set (In-Game Editor) . kenshi f12